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M¢ÁóÏ%–¢íbÎ5±Þ—› v"ø'J	>

>Œ´àa�žÝ"Ø`uZ¦^ % \ŸçTnlÐÚ‘	8
‚
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YDŠÙ¤þÎ¹Ã5¾' ¶ H­¤ðMm	v
|,ªÛê>ûj$®‹Ê! Ò 4‹¿þ�N	7	_	&�®äj©åQf•gÈ©ù, ™ Ï Ä?-+V]‡¥½IVfŸr:Å* ëÖ•Ë‡:‚»Ã}xE # : » .|Rw	é%èéëHÚ	0KŠ£È7ÌÔÖàY¬÷ â!WÂ6©	H
ïÊá|P(•Æ�œê ³ ù0åêí@Kø9eDæHÉ7 ˆ $�œÅX«	&
9^%ù2Ÿ.‘žI¢RB  ª d»JÚ
^©ç—N£*sk D Î–È*ä	�¯¶B·Ô3X1Lö yŠ¼ÔÜÚ"k’
÷36*NŸ±ÂT	®!
 ÈN½h=RXìé8 K„�zÀâ4YfQ€v	{	–	�µ»Å�Ý ‘ ÜzdäLÄD	³
A†fK\#3 ª¿~A#ÿ	#
J
Ì
{>ÅáçšŠk ? ü_~Ø>	Y	Ô"dô™mÏ1$‹ Œ 4o£õ

B
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éûw‘Øî.ÈZ‡:š-ï! À á õ V¾^¦ÒöM	M
‡
�LUÿx‚1ÜõŽ•ðG¸-3•N §õGõ8b¬	V	}®·~…‹äã’ÞÖ$‘
 âŸ�›¤ª�$ ÂÆç}À(	]	Iñ»ÀßëGÊ&“ÄÈgù ‚©¹OÇ\Ãæ‰¼  ¥Ú?E\fôGŽãåÖý,<ƒ²/+‰ä� , võ$	è	¾ÌrD¦´à'wÏœÛæ / Q üŒ×ê	úAãÌ_y7Ëí0ž� ‘¸s}¼Möè�  a /O0{MD{= �‘"<íðþ&›´ÚagÇ.ˆ*FÅØQF¹¦ó`ò g·ÏT…�ª1
p
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ÏÛt5J‘¨ÑåéI 9 u×=”‰÷C¶	=
À `Î$¡Òû!h_)t4¥a µ m,ï	7
•
­ãC{†¨+=ižeÂ9 º á äç5îÇ÷{6OdÓßŽ›CÂ«
 ‰ÍµøAMž¶ÁÓr ÇMy3eŽºÜèJ2 U¢
A
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ú­�ÛãY�ïÝ”M  Dá[ež 	ºêF;Ž©å . ` ûrìz³Ù-|CLxz�ÿ ft<�B	µ	o
B…öúg§Á¤Á x¡2dàZ€L�¨ÀâL pqÜÝÞßY„IJK›œ@ABy¦¿Àþ  *>  qGACNNNNNNGTC,CCAGGCCTGG,GATCCGGATC,CCWGGTACCWGG,CCANNNNNTGG,CCAGGNNNTGG,CCANNNCCTGG,CCAGGNCCTGG,GCACNNNAACGTTNNNGTGC,CACNNNGTG,CCNNNNNNNGG,AACNAACRYGTGCGTGC,GCACGCACRYGTTNGTT,GCACNAACRYGTTNGTGC,AACGCACRYGTGCGTT,GACNNNNNGTC,GAANNNNNNNTTGG,CCAANNNNNNNTTC,CACNNNNGTG,AACACNNNNGTGC,GCACNNNNGTGTT,GCANNNNNNTGC,GAACNNNNNNTCC,GGANNNNNNGTTC,CAGNNNCTG,CCAGGNNCTG,CAGNNCCTGG,CCWGGGCCC,GGGCCCWGG,CCWGGGCCCWGG,AACNNNNNNGTGCACNNNNNNGTT,GACNNNGTC,GAANNNNTTC,CCWGGTACC,GGTACCWGG,CCWGGWCCWGG,ACNNNNGTAYC,GRTACNNNNGT,CCWGGYRCCWGG,GAAGNNNNNNTAC,GTANNNNNNCTTC,AACGGCNNNGTGC,GCACNNNGCCGTT,GCACGGCNNNGTT,AACNNNGCCGTGC,CGANNNNNNTGC,GCANNNNNNTCG,CGATCNNNNTGC,GCANNNNGATCG,TGANNNNNNTCA,TGATCNNNNTCA,TGANNNNGATCA,TGATCNNGATCA,AACCTGCNNGTGC,GCACNNGCAGGTT,GCACCTGCNNGTT,AACNNGCAGGTGC,GCCNNNNNGGC,AACNNNNNNGTGCMC,GKGCACNNNNNNGTT,CCWGGNCCWGG,AACTGGGNNGTGC,GCACNNCCCAGTT,GCACTGGGNNGTT,AACNNCCCAGTGC,GACNNNNGTC,GAGNNNNNCTC,CCWGGTCTC,GAGACCWGG,GATNNNNATC,GATCNNNATC,GATNNNGATC,GATCNNGATC,CCWGGCGCCWGG,ACNNNNNCTCC,GGAGNNNNNGT,AACNNNNNNGTGCAG,CTGCACNNNNNNGTT,GATCATGATC,CCWGGNNCCWGG,AACTGGNNNGTGC,GCACNNNCCAGTT,GCACTGGNNNGTT,AACNNNCCAGTGC,AACNAACCGGTGCGTGC,GCACGCACCGGTTNGTT,GCACNAACCGGTTNGTGC,AACGCACCGGTGCGTT,GCANNNNNTGC,GCACNNNNNNGTTCGAACNNNNNNGTGC,CCTNNNNNAGG,GCNNNNNNNGC,CCANNNNNNTGG,CCAGGNNCCTGG,CCTGGCCAGG,CAANNNNNGTGG,CCACNNNNNTTG,TTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAA,GCACNNNNNNGTTTAAACNNNNNNGTGC,CCAGGNCCY,RGGNCCTGG,CCWGGGNCCTGG,CCAGGNCCCWGG,AAGNNNNNCTT,GAYNNNNNVTC,GABNNNNNRTC,GAYNNNNNRTC,GATCNNNNVTC,GABNNNNGATC,GAYNNNNGATC,GATCNNNNRTC,GATCNNNGATC,GTYAACNNNNNNGTGC,GCACNNNNNNGTTRAC,GCACNNNNNNGTTAACNNNNNNGTGC,GATCNGATC,TAACTATAACGGTCCTAAGGTAGCGA,TCGCTACCTTAGGACCGTTATAGTTA,CTCTCTTAAGGTAGC,GCTACCTTAAGAGAG,TAGGGATAACAGGGTAAT,ATTACCCTGTTATCCCTA,GTTAACNNNNNNGTGC,GCACNNNNNNGTTAAC,AACNAACGCGTGCGTGC,GCACGCACGCGTTNGTT,GCACNAACGCGTTNGTGC,AACGCACGCGTGCGTT,TCCAACNNNNNNGTGC,GCACNNNNNNGTTGGA,CAYNNNNRTG,AACAYNNNNGTGC,GCACNNNNRTGTT,GTTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAAC,CCWGGCGCC,GGCGCCWGG,CCWGGNNCC,GGNNCCWGG,GATCGCGATC,AACNAACATGTGCGTGC,GCACGCACATGTTNGTT,GCACNAACATGTTNGTGC,AACGCACATGTGCGTT,TGGCAAACAGCTATTATGGGTATTATGGGT,ACCCATAATACCCATAATAGCTGTTTGCCA,ATCTATGTCGGGTGCGGAGAAAGAGGTAATGAAATGG,CCATTTCATTACCTCTTTCTCCGCACCCGACATAGAT,AACNNGCACGTGCNNGTT,GAACNNNNNCTC,GAGNNNNNGTTC,CCAGGWCCY,RGGWCCTGG,CCWGGGWCCTGG,CCAGGWCCCWGG,CCAGGWCCTGG,TTATAACNNNNNNGTGC,GCACNNNNNNGTTATAA,GCACNNNNNNGTTATAACNNNNNNGTGC,GAACNNNNNNTAC,GTANNNNNNGTTC,GGCCNNNNNGGCC,AACNNACTAGTGC,GCACTAGTNNGTT,AACTAGTNNGTGC,GCACNNACTAGTT,AACNAACTAGTGCGTGC,GCACGCACTAGTTNGTT,GCACNAACTAGTTNGTGC,AACGCACTAGTGCGTT,AACNNNAACGTGCNNGTGC,GCACNNGCACGTTNNNGTT,GCACCCANNNGTT,AACNNNTGGGTGC,TTAACNNNNNNGTGC,GCACNNNNNNGTTAA,CACNNNNNNTCC,GGANNNNNNGTG,CACNNNNGATCC,GGATCNNNNGTG,GATCTAGATC,CCANNNNNNNNNTGG,CCAGGCCT,AGGCCTGG,CCTCGAGG,GATCCGGA,TCCGGATC,GGCGCGCC,GCGATCGC,CCWGGWCC,GGWCCWGG,GATCGATC,GATCATGA,TCATGATC,GCGGCCGC,CCTGGCCR,YGGCCAGG,CCWGGNCC,GGNCCWGG,GGCCGGCC,RTGCGCAY,GATCNNGA,TCNNGATC,CGCGCGCG,CCTGGCCA,TGGCCAGG,CGCCGGCG,GTTTAAAC,GATCGCGA,TCGCGATC,TTAATTAA,VCTCGAGB,CCTGCAGG,CRCCGGYG,CGTCGACG,ATTTAAAT,GCCCGGGC,GATCTAGA,TCTAGATC,CACCTGC,GCAGGTG,CCTNAGG,GATCGAT,ATCGATC,CCTCAGC,GCTGAGG,GCTNAGC,CCTNAGC,GCTNAGG,GCTCTTC,GAAGAGC,GGTNACC,CGGWCCG,ACCWGGT,RGGNCCY,CCTGGAG,CTCCAGG,GGTGATC,GATCACC,GATCNGA,TCNGATC,GGGWCCC,GAAGATC,GATCTTC,CCCWGGG,TCCNGGA,TCCWGGA,RGGWCCY,TTATAA,AGGCCT,GACGTC,GTMKAC,TCCGGA,TGCGCA,ACCTGC,GCAGGT,GGTACC,AGTACT,GGYRCC,CCGCTC,GAGCGG,AACGTT,YGGCCR,RAATTY,CTGAAG,CTTCAG,CACGTG,GRCGYC,AGCGCT,CTTAAG,ACRYGT,ACCGGT,ACTAGT,CACGTC,GACGTG,GWGCWC,GTGCAC,CYCGRG,GGGCCC,ATTAAT,CCTAGG,TTCGAA,GCTAGC,GKGCMC,TGGCCA,GGATCC,GRGCYC,ATCGAT,CACGAG,CTCGTG,GGCGCC,GAAGAC,GTCTTC,GCATGC,GTATCC,GGATAC,TGATCA,ACTGGG,CCCAGT,CTRYAG,RGCGCY,AGATCT,GGNNCC,CTGGAG,CTCCAG,CTTGAG,CTCAAG,CGATCG,GGTCTC,GAGACC,YACGTR,CCNNGG,GAATGC,GCATTC,WCCGGW,GCAATG,CATTGC,RCCGGY,GCGCGC,GAGGAG,CTCCTC,CGGCCG,CCCAGC,GCTGGG,GTGCAG,CTGCAC,CGRYCG,CGTACG,CGTCTC,GAGACG,CCATGG,TCGCGA,GDGCHC,TGTACA,TCATGA,ACATGT,GTATAC,CCWWGG,CTCTTC,GAAGAG,GCNNGC,CCRYGG,GTTAAC,RCATGY,TACGTA,RGATCY,GCGATG,CATCGC,GCAGTG,CACTGC,CCCGGG,CCGCGG,TTTAAA,GGCGGA,TCCGCC,GAGCTC,GATATC,CTGRAG,CTYCAG,CAGCAG,CTGCTG,GAATTC,ATGCAT,CATATG,GTYRAC,AAGCTT,GTNNAC,TCNNGA,CAATTG,ACGCGT,TCCRAC,GTYGGA,GCCGGC,CMGCKG,GCCGAG,CTCGGC,CTCGAG,CTGCAG,CAGCTG,GTCGAC,CTYRAG,AATATT,GATCGA,TCGATC,GACCGA,CACCCA,TCGGTC,TGGGTG,WGTACW,TARCCA,TGGYTA,TCTAGA,GGATC,GATCC,CCWGG,GTCTC,GAGAC,GCWGC,GGNCC,CCSGG,GGTGA,TCACC,GGWCC,GCAGC,GCTGC,CCATC,GATGG,ACGGC,GCCGT,GCNGC,CCNGG,GCATC,GATGC,ACTGG,CCAGT,GGATG,CATCC,CTCAG,CTGAG,GGGAC,GTCCC,ACNGT,CTNAG,CAGTG,CACTG,GACGC,GCGTC,CCCGC,GCGGG,GANTC,CGWCG,TCNGA,CCTTC,GAAGG,GTNAC,GAAGA,TCTTC,GAGTC,GACTC,GTSAC,GAWTC,GCSGC,CASTG,ATGAA,TTCAT,ACGGA,TCCGT,CGCG,CCGC,GCGG,GTAC,AGCT,GCGC,CTAG,GATC,GGCC,CCGG,CATG,RGCY,YATR,ACGT,TGCA,AATT,CCTC,GAGG,TTAA,ASST,TCGA                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
                                                                                                                                                                                                                                                                                                 	                                          
               J   [         3         (   P                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
                                                                                                     	              
     J [   3   ( P   l¸  mj  mx  mœ  pÂ  tP  yfZ ócC	ù!. û¸þÞµ	Cúê_ÅÜuûeÔìD˜Íî
~ª
Oì—îjêŠð�­Èòô6ð`”÷#wº,hì1
dýÐ74u¿×
uuGÊerxì°û£áu]0á‰y‚£8ÙŠòIGGIç‡à!- 8ŠÍ¤±RäÝÂ#VˆÓÖXKÓýFÇ´[¸Á‰N[Ð´§:
^\þú @´`kSÁÝŒ	Ý	
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This inhibition can be relieved by adding lactose or isopropyl-Î²-D-thiogalactopyranoside (IPTG).&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="bound_moiety"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;lac&lt;/i&gt; repressor encoded by &lt;i&gt;lacI&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="2" name="lac promoter" directionality="2" type="promoter" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment name="-10" range="4062-4068" color="#ffffff" type="standard"/><Segment range="4069-4086" color="#ffffff" type="standard"/><Segment name="-35" range="4087-4092" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;promoter for the &lt;i&gt;E. coli lac&lt;/i&gt; operon&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="1" name="AmpR" directionality="2" translationMW="31558.16" type="CDS" swappedSegmentNumbering="1" allowSegmentOverlaps="0" cleavageArrows="5966" readingFrame="-1" consecutiveTranslationNumbering="1" hitsStopCodon="1" detectionMode="exactProteinMatch"><Segment range="5175-5966" color="#ccffcc" type="standard" translated="1"/><Segment name="signal sequence" range="5967-6035" color="#ccffcc" type="standard" translated="1"/><Q name="product"><V text="&lt;html&gt;&lt;body&gt;Î²-lactamase&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;confers resistance to ampicillin, carbenicillin, and related antibiotics&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="codon_start"><V int="1"/></Q><Q name="gene"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;bla&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q></Feature><Feature recentID="0" name="AmpR promoter" directionality="2" type="promoter" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="6036-6140" color="#ffffff" type="standard"/><Q name="gene"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;bla&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q></Feature></Features>
  !¢<?xml version="1.0"?><Primers nextValidID="16"><HybridizationParams minContinuousMatchLen="10" allowMismatch="1" minMeltingTemperature="40"/><Primer recentID="0" name="Amp-R" sequence="ATAATACCGCGCCACATAGC" description="Ampicillin resistance gene, reverse primer"><BindingSite location="5797-5816" boundStrand="0" annealedBases="ATAATACCGCGCCACATAGC" meltingTemperature="58"><Component hybridizedRange="5797-5816" bases="ATAATACCGCGCCACATAGC"/></BindingSite><BindingSite simplified="1" location="5797-5816" boundStrand="0" annealedBases="ATAATACCGCGCCACATAGC" meltingTemperature="58"><Component hybridizedRange="5797-5816" bases="ATAATACCGCGCCACATAGC"/></BindingSite></Primer><Primer recentID="1" name="F1ori-F" sequence="GTGGACTCTTGTTCCAAACTGG" description="F1 origin, forward primer"><BindingSite location="1487-1508" boundStrand="1" annealedBases="GTGGACTCTTGTTCCAAACTGG" meltingTemperature="57"><Component hybridizedRange="1487-1508" bases="GTGGACTCTTGTTCCAAACTGG"/></BindingSite><BindingSite simplified="1" location="1487-1508" boundStrand="1" annealedBases="GTGGACTCTTGTTCCAAACTGG" meltingTemperature="57"><Component hybridizedRange="1487-1508" bases="GTGGACTCTTGTTCCAAACTGG"/></BindingSite></Primer><Primer recentID="2" name="F1ori-R" sequence="AGGGAAGAAAGCGAAAGGAG" description="F1 origin, reverse primer"><BindingSite location="1699-1718" boundStrand="0" annealedBases="AGGGAAGAAAGCGAAAGGAG" meltingTemperature="57"><Component hybridizedRange="1699-1718" bases="AGGGAAGAAAGCGAAAGGAG"/></BindingSite><BindingSite simplified="1" location="1699-1718" boundStrand="0" annealedBases="AGGGAAGAAAGCGAAAGGAG" meltingTemperature="57"><Component hybridizedRange="1699-1718" bases="AGGGAAGAAAGCGAAAGGAG"/></BindingSite></Primer><Primer recentID="3" name="L4440" sequence="AGCGAGTCAGTGAGCGAG" description="L4440 vector, forward primer"><BindingSite location="4244-4261" boundStrand="1" annealedBases="AGCGAGTCAGTGAGCGAG" meltingTemperature="58"><Component hybridizedRange="4244-4261" bases="AGCGAGTCAGTGAGCGAG"/></BindingSite><BindingSite simplified="1" location="4244-4261" boundStrand="1" annealedBases="AGCGAGTCAGTGAGCGAG" meltingTemperature="58"><Component hybridizedRange="4244-4261" bases="AGCGAGTCAGTGAGCGAG"/></BindingSite></Primer><Primer recentID="4" name="M13 Forward" sequence="TGTAAAACGACGGCCAGT" description="In lacZ gene. Also called M13-F20 or M13 (-21) Forward"><BindingSite location="1949-1966" boundStrand="0" annealedBases="TGTAAAACGACGGCCAGT" meltingTemperature="56"><Component hybridizedRange="1949-1966" bases="TGTAAAACGACGGCCAGT"/></BindingSite><BindingSite simplified="1" location="1949-1966" boundStrand="0" annealedBases="TGTAAAACGACGGCCAGT" meltingTemperature="56"><Component hybridizedRange="1949-1966" bases="TGTAAAACGACGGCCAGT"/></BindingSite></Primer><Primer recentID="5" name="M13 Reverse" sequence="CAGGAAACAGCTATGAC" description="In lacZ gene. Also called M13-rev"><BindingSite location="4013-4029" boundStrand="1" annealedBases="CAGGAAACAGCTATGAC" meltingTemperature="49"><Component hybridizedRange="4013-4029" bases="CAGGAAACAGCTATGAC"/></BindingSite><BindingSite simplified="1" location="4013-4029" boundStrand="1" annealedBases="CAGGAAACAGCTATGAC" meltingTemperature="49"><Component hybridizedRange="4013-4029" bases="CAGGAAACAGCTATGAC"/></BindingSite></Primer><Primer recentID="6" name="M13/pUC Forward" sequence="CCCAGTCACGACGTTGTAAAACG" description="In lacZ gene"><BindingSite location="1935-1957" boundStrand="0" annealedBases="CCCAGTCACGACGTTGTAAAACG" meltingTemperature="61"><Component hybridizedRange="1935-1957" bases="CCCAGTCACGACGTTGTAAAACG"/></BindingSite><BindingSite simplified="1" location="1935-1957" boundStrand="0" annealedBases="CCCAGTCACGACGTTGTAAAACG" meltingTemperature="61"><Component hybridizedRange="1935-1957" bases="CCCAGTCACGACGTTGTAAAACG"/></BindingSite></Primer><Primer recentID="7" name="M13/pUC Reverse" sequence="AGCGGATAACAATTTCACACAGG" description="In lacZ gene"><BindingSite location="4026-4048" boundStrand="1" annealedBases="AGCGGATAACAATTTCACACAGG" meltingTemperature="58"><Component hybridizedRange="4026-4048" bases="AGCGGATAACAATTTCACACAGG"/></BindingSite><BindingSite simplified="1" location="4026-4048" boundStrand="1" annealedBases="AGCGGATAACAATTTCACACAGG" meltingTemperature="58"><Component hybridizedRange="4026-4048" bases="AGCGGATAACAATTTCACACAGG"/></BindingSite></Primer><Primer recentID="8" name="pBluescriptSK" sequence="TCTAGAACTAGTGGATC" description="For pBluescript vector"><BindingSite location="3921-3937" boundStrand="1" annealedBases="TCTAGAACTAGTGGATC" meltingTemperature="44"><Component hybridizedRange="3921-3937" bases="TCTAGAACTAGTGGATC"/></BindingSite><BindingSite simplified="1" location="3921-3937" boundStrand="1" annealedBases="TCTAGAACTAGTGGATC" meltingTemperature="44"><Component hybridizedRange="3921-3937" bases="TCTAGAACTAGTGGATC"/></BindingSite></Primer><Primer recentID="9" name="pBR322ori-F" sequence="GGGAAACGCCTGGTATCTTT" description="pBR322 origin, forward primer"><BindingSite location="4495-4514" boundStrand="1" annealedBases="GGGAAACGCCTGGTATCTTT" meltingTemperature="56"><Component hybridizedRange="4495-4514" bases="GGGAAACGCCTGGTATCTTT"/></BindingSite><BindingSite simplified="1" location="4495-4514" boundStrand="1" annealedBases="GGGAAACGCCTGGTATCTTT" meltingTemperature="56"><Component hybridizedRange="4495-4514" bases="GGGAAACGCCTGGTATCTTT"/></BindingSite></Primer><Primer recentID="10" name="pBRforEco" sequence="AATAGGCGTATCACGAGGC" description="pBR322 vectors, upsteam of EcoRI site, forward primer"><BindingSite location="6207-6225" boundStrand="0" annealedBases="AATAGGCGTATCACGAGGC" meltingTemperature="57"><Component hybridizedRange="6207-6225" bases="AATAGGCGTATCACGAGGC"/></BindingSite><BindingSite simplified="1" location="6207-6225" boundStrand="0" annealedBases="AATAGGCGTATCACGAGGC" meltingTemperature="57"><Component hybridizedRange="6207-6225" bases="AATAGGCGTATCACGAGGC"/></BindingSite></Primer><Primer recentID="11" name="pGEX 3'" sequence="CCGGGAGCTGCATGTGTCAGAGG" description="pGEX vectors, reverse primer"><BindingSite location="28-50" boundStrand="1" annealedBases="CCGGGAGCTGCATGTGTCAGAGG" meltingTemperature="66"><Component hybridizedRange="28-50" bases="CCGGGAGCTGCATGTGTCAGAGG"/></BindingSite><BindingSite simplified="1" location="28-50" boundStrand="1" annealedBases="CCGGGAGCTGCATGTGTCAGAGG" meltingTemperature="66"><Component hybridizedRange="28-50" bases="CCGGGAGCTGCATGTGTCAGAGG"/></BindingSite></Primer><Primer recentID="12" name="pHybLex-R" sequence="GAGTCACTTTAAAATTTGTATACAC" description="ADH terminator, reverse primer"><BindingSite location="3781-3805" boundStrand="1" annealedBases="GAGTCACTTTAAAATTTGTATACAC" meltingTemperature="51"><Component hybridizedRange="3781-3805" bases="GAGTCACTTTAAAATTTGTATACAC"/></BindingSite><BindingSite simplified="1" location="3781-3805" boundStrand="1" annealedBases="GAGTCACTTTAAAATTTGTATACAC" meltingTemperature="51"><Component hybridizedRange="3781-3805" bases="GAGTCACTTTAAAATTTGTATACAC"/></BindingSite></Primer><Primer recentID="13" name="pRS-marker" sequence="CGGCATCAGAGCAGATTGTA" description="pRS vectors, use to sequence yeast selectable marker"><BindingSite location="150-169" boundStrand="0" annealedBases="CGGCATCAGAGCAGATTGTA" meltingTemperature="54"><Component hybridizedRange="150-169" bases="CGGCATCAGAGCAGATTGTA"/></BindingSite><BindingSite simplified="1" location="150-169" boundStrand="0" annealedBases="CGGCATCAGAGCAGATTGTA" meltingTemperature="54"><Component hybridizedRange="150-169" bases="CGGCATCAGAGCAGATTGTA"/></BindingSite></Primer><Primer recentID="14" name="T3" sequence="GCAATTAACCCTCACTAAAGG" description="T3 promoter, forward primer"><BindingSite location="3974-3994" boundStrand="1" annealedBases="GCAATTAACCCTCACTAAAGG" meltingTemperature="52"><Component hybridizedRange="3974-3994" bases="GCAATTAACCCTCACTAAAGG"/></BindingSite><BindingSite simplified="1" location="3974-3994" boundStrand="1" annealedBases="GCAATTAACCCTCACTAAAGG" meltingTemperature="52"><Component hybridizedRange="3974-3994" bases="GCAATTAACCCTCACTAAAGG"/></BindingSite></Primer><Primer recentID="15" name="T7" sequence="TAATACGACTCACTATAGGG" description="T7 promoter, forward primer"><BindingSite location="1976-1995" boundStrand="0" annealedBases="TAATACGACTCACTATAGGG" meltingTemperature="49"><Component hybridizedRange="1976-1995" bases="TAATACGACTCACTATAGGG"/></BindingSite><BindingSite simplified="1" location="1976-1995" boundStrand="0" annealedBases="TAATACGACTCACTATAGGG" meltingTemperature="49"><Component hybridizedRange="1976-1995" bases="TAATACGACTCACTATAGGG"/></BindingSite></Primer></Primers>
  ,<Notes>
<UUID>d45ceb09-d5c2-4384-8dea-1e959805b7a2</UUID>
<Type>Synthetic</Type>
<ConfirmedExperimentally>0</ConfirmedExperimentally>
<CustomMapLabel>PTEF1-yEGFPCLN2PEST-pRS406</CustomMapLabel>
<UseCustomMapLabel>1</UseCustomMapLabel>
<Description>TEF promoter driven GFP expression.</Description>
<Created UTC="0:22:31">2021.5.13</Created>
<LastModified UTC="5:36:44">2023.5.5</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
<References>
<Reference authors="Williams TC, Espinosa MI, Nielsen LK, Vickers CE" title="Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiae." journal="Microb Cell Fact. 2015 Apr 1;14:43. doi: 10.1186/s12934-015-0223-7." pubMedID="25886317"/>
</References>
</Notes>
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%Ù²ŒcÅvn+b½ÂÞ¢’…#¸`"~;ü•F}P=Uø*8ÚO    Mäâ…Uå ã–H  sHÇÕ±Ägû    YZ   -<AlignableSequences trimStringency="Medium"/>  !<AdditionalSequenceProperties><UpstreamStickiness>0</UpstreamStickiness><DownstreamStickiness>0</DownstreamStickiness><UpstreamModification>FivePrimePhosphorylated</UpstreamModification><DownstreamModification>FivePrimePhosphorylated</DownstreamModification></AdditionalSequenceProperties>
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   —<?xml version="1.0"?><Primers nextValidID="0"><HybridizationParams minContinuousMatchLen="10" allowMismatch="1" minMeltingTemperature="40"/></Primers>
  «<Notes>
<UUID>9b481668-3718-4976-9dbb-8654dfd4b783</UUID>
<Type>Synthetic</Type>
<ConfirmedExperimentally>0</ConfirmedExperimentally>
<CustomMapLabel>PTEF1-yEGFPCLN2PEST-pRS406</CustomMapLabel>
<UseCustomMapLabel>1</UseCustomMapLabel>
<Description>TEF promoter driven GFP expression.</Description>
<Created UTC="0:22:31">2021.5.13</Created>
<LastModified UTC="5:36:56">2023.5.5</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
<References>
<Reference journal="Microb Cell Fact. 2015 Apr 1;14:43. doi: 10.1186/s12934-015-0223-7." title="Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiae." authors="Williams TC, Espinosa MI, Nielsen LK, Vickers CE" volume="14:43. doi" journalName="Microb Cell Fact." pubMedID="25886317" type="Journal Article" date="2015-04-1" pages=" 10.1186/s12934-015-0223-7"/>
</References>
</Notes>
  Y     –         
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   )<?xml version="1.0"?><CustomEnzymeSets/>
